ESR Blog post #8 "Elegy and Eulogy of Ovarian Follicles" by Pritha Dey, ESR3, UMIL
History tells us that the first sign of cell death was observed in the mid-1800s. Whereas regulated cell death came to light in the late 1900s, as what we so commonly know now to be apoptosis. Since then, the terms ‘apoptosis’ and ‘autophagy’ have become synchronous with ‘cell death’.
For a long time thereafter, scientists remained obsessed with the morphological presentations and the biochemical relay exhibited by these phenomena and progressively constructed new categories of cell death modes. In the article cited below, we provide an overview of the chaotic classification of some of these mechanisms in the mammalian ovary and the resident population of compartmentalized ovarian follicles, thereby setting the undertone for our research objective (ESR3).
Figure: Visualization of the publication statistics of some of the different modes of programmed cell death queried on PubMed. Pink: Number of ovary-related studies related to specific PCD.
Blue: Total number of studies related to a specific PCD.
On the blue/pink bar border: Year of 1st ovary-related publication
Cited from: Dey, Pritha, and Alberto Maria Luciano. "A century of programmed cell death in the ovary: a commentary." Journal of assisted reproduction and genetics (2022): 1-4.